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Research Projects


The Center for Health Outcomes and Policy Research at the University of Pennsylvania School of Nursing merits the greatest support possible.  It is an unparalleled resource to the profession and discipline of nursing, and an invaluable source of innovation to healthcare in the USA and abroad

National Institute of Nursing Research supports and conducts clinical and basic research and research training on health and illness, research that spans and integrates the behavioral and biological sciences, and that develops the scientific basis for clinical practice. 

  • Panel Study of Effects of Changes in Nursing on Patient Outcomes
    PI: Dr. Linda H. Aiken

In the 2015 study, we replicated measurements made in 2006 across approximately 665 hospitals and hundreds of nursing homes and home care agencies in CA, FL, NJ and PA; and, in 1999 with over 200 hospitals in Pennsylvania in order to examine organizational-level changes over time in nurse inputs in education, staffing, skill mix, and work environment. 

  • Alzheimer’s Disease and its related Dementias (AD/ADRD)-focused Administrative supplement 
    Subaward PI: Dr. Olga Jarrín, Rutgers University.

The supplmental study will determine the impact of nurse education, staffing, skill mix, and work environment on trajectories of care and outcome for people living with Alzheimer’s disease and related dementias by identifying actionable nursing factors that can be leveraged to increase access to high quality dementia care for the U.S. population.   

  • Comparing Quality and Cost of Care Across Nursing Environments
    PI: Matthew D. McHugh, PhD, JD, MPH, RN, CRNP, FAAN, Co-Principal Investigator with Jeffrey H. Silber, MD, PhD.

The goal of this three-year NIH funded study is to answer a fundamental question in nursing: Is there an economic case with respect to quality, cost, and value for improving the nursing environment. Drs. Linda Aiken, Paul Rosenbaum, and Herbert Smith are co-investigators.

  • The Impact of Nursing on In-Hospital Cardiac Arrest Patient Outcomes
    PI: Matthew D. McHugh
    , PhD, JD, MPH, RN, CRNP, FAAN; Co-investigators include Drs. Linda Aiken and Robert Berg.

This three-year NIH funded project explores in-hospital cardiac arrests, focusing on the relationship between nursing and post-arrest outcomes. 



National Institute on Minority Health and Health Disparities is one of the 27 Institutes and Centers of the National Institutes of Health (NIH), the nation’s premiere medical research agency. NIMHD’s work touches the lives of millions of Americans burdened by disparities in health status and health care delivery.

  • The Impact of Nursing on Racial Disparities in Surgical Outcomes 
    Co-PI: Dr. Matthew D. McHugh

We will separately determine the effects of patient, surgeon, nursing, and hospital characteristics on racial disparities, closely examine the relationship between nursing and disparities in specific procedure and patient groups, and learn whether changes in nursing resources over time have had consequences for racial disparities in surgery outcomes.

  • Disparities in the Outcomes and Processes of Care for In-Hospital Cardiac Arrest: The Role of Differences in the Organization and Delivery of Nursing 
    PI: Dr. J. Margo Brooks Carthon

The aim of the grant is to examine the relationship between the organization and delivery of nursing care and in-hospital cardiac arrest (ICHA) outcomes among Black patients.


American Nurses Foundation (ANF) is the charitable and philanthropic arm of the American Nurses Association. The foundation accomplishes its mission to improve healthcare and support the 3.6 million nurses across the US by raising funds and developing and managing grants to support advances in research, education, and clinical practice.

  • Predicting Likely Candidates for Successful Magnet Applications Among Hospitals in Europe
    PI: Dr. Linda H.  Aiken

The purpose of the one year study funded is to distinguish hospitals in Europe that are Magnet-like and near-Magnets in order to inform strategies for improving Magnet Journey success in Europe

  • Examination of Burdensome Transitions at End-Of-Life among Older Adults with Cancer
    PI: Dr. Jessica Rearden

The Maura C. Ryan Gerontological Nursing Research Scholarship will illuminate multi-level predictors of burdensome transitions and identify disparities, as well as current and optimal uses of hospice care to reduce. burdensome transitions.

  • Job Dissatisfaction, Burn out and Intent to Leave among Black Nurses: The Role of the Work Environment
    PI: Dr.  J. Margo Brooks Carthon

Our proposal examines the relationship between clinical work environments and job outcome differences between Black and White nurses.

  • Effects of Nurse Education, Skill Mix, Staffing Ratios and Work Environments on Rural Hospital Patient Outcomes
    PI: Dr. Jessica Smith

This study will help explicate the importance of well-prepared nurses and high quality nurse work environments for rural hospital patient outcomes.


Recently Completed

The Centers for Medicare and Medicaid Services (CMS) is a federal agency within the US Department of Health and Human Services (HHS) that administers Medicare and works in partnership with state governments to administer Medicaid. One of five hospitals selected from the United States for the reasonable cost of providing clinical training to advanced practice registered nursing (APRN) students added as a result of the demonstration. Project Title: Graduate Nurse Education DemonstrationDr. Linda H. Aiken, Executive Committee for the Graduate Nurse Network of Greater Philadelphia

National Council of State Boards of Nursing (NCSBN) is an independent, not-for-profit organization through which boards of nursing act and counsel togetherThis study describes recent trends in nurse immigration and the non-US educated nurse workforce in the US and determine the degree to which employment of non-US educated nurses in US hospitals adversely affects nurse and patient outcomes. Project Titke: Contributions of Foreign Educated Nurses to Quality Care in the US,  Matthew D. McHugh, PhD, JD, MPH, RN, CRNP, FAAN (PI)