The Baxter International Foundation’s Episteme Award acknowledges a"major break-through in nursing knowledge development that has resulted in a significant and recognizable benefit to the public" and is presented to a person or team for highly significant research. Penn Nursing is home to seven award winners, more than any other school of nursing, including Dorothy Brooten (1989), Lois K. Evans and Neville E. Strumpf (1995), Ann Burgess (1999), Linda H. Aiken (2001), Loretta Sweet Jemmott (2007), and Mary D. Naylor (2009).

The Chapter is also the recipient of the Key Award  and the Showcase of
Excellence Award, both in 2008.