Posted April 2012 Cancer and Clinical TrialsIn one of the first studies of its kind, University of Pennsylvania School of Nursing researchers have identified what cancer patients consider the “benefits and burdens” of participating in clinical research trials. From their findings, the researchers developed a model of the five elements of decision-making (physical, psychological, economic, familial, and social) that patients with cancer use to determine whether to participate or remain in a clinical trial.
These findings can help researchers address factors leading to research participation and in ensuring voluntary, informed consent in clinical trials, explained lead author Connie M. Ulrich, PhD, RN, of Penn Nursing. “Clinical research is imperat...
Posted June 2010 Life During and After CancerThere seems hardly a facet of life after cancer and cancer screening that Dr. Deborah Bruner has not researched. Her work spans cancer related screening behaviors, decision-making related to screening and treatment, quality of life in prostate, gynecologic, brain, and head and neck cancers and gender differences in treatment outcomes. She has been a pioneer in measuring the patient experience in cancer clinical trials.
One of her major studies has been on the reaction of spouses to prostate cancer screening and treatment. Wives, she noted, tend to want doctors to take more aggressive options than their husbands do. Husbands, Dr. Bruner has found, initially say they want to preserve their quality of life, rather than extending their lives when interviewed alone; but when the husband hears th...