Publications
Karen Badellino, PhD, RN
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Books
Badellino, K., Jin, W., and Rader, D.J. (2004). Endothelial lipase: a novel drug target for HDL and atherosclerosis?. New York: Wiley-VCH.
Book Chapters
Badellino, K. and Jin, W. (2005). Endothelial lipase & the regulation of HDL metabolism. In Packard, C.J. and Rader, D.J. (eds.) (Eds.), Advances in Translational Medical Science: Lipids and Atherosclerosis. xxxx: xxxx.
Badellino, K., Jin, W., Rader, D.J. (2004). Endothelial lipase: a novel drug target for HDL and atherosclerosis?. In Muller, G. and Petry, S. (ed.) (Eds.), Lipases and Phospholipases in Drug Development. New York, NY: Wiley-VCH.
Journals/Periodicals
Compher, C.W., Badellino, K.O. & Boullata, J.I. (2008). Vitamin d and the bariatric surgical patient: a review. Obesity Surgery, 18(2), 220-224.
Badellino, K.O., Wolfe, M.L., Reilly, M.P. & Rader, D.J. (2008). Endothelial lipase is increased in vivo by inflammation in humans. Circulation, 117(5), 678-85.
Schwertz, D.W. & Badellino, K.O. (2008). High-dose statin therapy for secondary prevention of stroke: stroke prevention by aggressive reduction in cholesterol levels study review. Journal of Cardiovascular Nursing, 23(1), 8-13.
Paradis, ME., Badellino, K.O., Rader, D.J., Tchernof, A., Richard, C., LuuThe, V., Bergeron, J., Archer, W.R., Couture, P., Bergeron, N. and Lamarche, B. (2006). Visceral adipolisty and endothelial lipase. Journal of Clinical Endocrinology & Metabolism, 91(9), 3538-43.
Paradis, M.E., Badellino, K.O., Rder, D.J., Deshaies, Y., Couture, Pa., Archer, W.R., Bergeron, N., Lamarche, B. (2006). Endothelial lipase is associataed with inflammation in humans. Journal of Lipid Research, 47(12), 2808-13.
Badellino, K.O., Wolfe, M.L., Reilly, M.P., Rader, D.J. (2006). Endothelial lipase concentrations are increased in metabolic syndrome and associated with coronary atherosclerosis. PLoS Medicine, 3(2), e22.
Ruel IL, Lamarche B, Mauger JF, Badellino KO, Cohn JS, Marcil M, Couture P. (2005). Effect of fenofibrate on plasma lipoprotein composition and kinetics in patients with complete hepatic lipase deficiency. Arteriosclerosis Thrombosis, and Vascular Biology, 25(12), 2600-7.
Sinha, D., Badellino, K.O., Marchinkiewicz, M., & Walsh, P.N. (2004). Allosteric modification of factor XIa functional activity upon binding to polyanions. Biochemistry, 43(23), 7593-7600.
Badellino, K.O., & Rader, D.J. (2004). The role of endothelial lipase in high-density lipoprotein metabolism. Current Opinion in Cardiology, 19(4), 392-395.
Miller, G.C., Long, C.J., Bojilova, E.D., Marchadier, D., Badellino, K.O., Blanchard, N., et al (2004). Role of N-linked glycosylation in the secretion and activity of endothelial lipase. Journal of Lipid Research, 45(11), 2080-7.
Baglia, F. A., Badellino, K. O., Li, C. Q., Lopez, J. A., & Walsh, P. N. (2002). Factor XI binding to the platelet glycoprotein Ib-IX-V complex promotes factor XI activation by thrombin. Journal of Biological Chemistry, 277(3), 1662-1668.
Badellino, K. O., & Walsh, P. N. (2001). Localization of a heparin binding site in the catalytic domain of factor XIa. Biochemistry, 40(25), 7569-7580.
Ho, D., H., Badellino, K., Baglia, F.A., Sun, M.f., Zhao, M.M., Gialini, D., et al (2000). The role of high molecular weight kininogen and prothrombin as cofactors in the binding of factor XI A3 domain to the platelet surface. Journal of Biological Chemistry, 275(33), 25139-25145.
Baglia, F.A., Badellino, K.O., Ho, D.H., Dasari, V.R., & Walsh, P.N. (2000). A binding site for the kringle II domain of prothrombin in the apple 1 domain of factor XI. Journal of Biological Chemistry, 275(41), 31954-31962.
Badellino, K.O., & Walsh, P.N. (2000). Protease nexin II interactions with coagulation factor XIa are contained with in the Kunitz protease inhibitor domain of protease nexin II and the factor XIa catalytic domain. Biochemistry, 39(16), 4769-4777.
Ho, D.H., Badellino, K., Baglia, F.A., & Walsh, P.N. (1998). A binding site for heparin in the apple 3 domain of factor XI. Journal of Biological Chemistry, 273(26), 16382-16390.
Kowalska, M.A., & Badellino, K. (1994). beta-Amyloid protein induces platelet aggregation and supports platelet adhesion. Biochemical and Biophysical Research Communications, 205(3), 1829-1835.