Margaret C Souders, PhD, CRNP
Assistant Professor of Human Genetics

Contact Information
University of Pennsylvania School of Nursing
Room 309 Fagin Hall
418 Curie Blvd.
Philadelphia, Pennsylvania 19104-4217
tel: (215) 898-1935

Dr. Souders received her baccalaureate in nursing and master’s degree in pediatric acute/chronic nursing in 1996, her doctorate in nursing in 2008, and completed a postdoctoral fellowship in sleep medicine, all from the University of Pennsylvania, School of Nursing. Dr. Souders previously held an appointment in the Child Development Department and was Dysmorphology Supervisor for the Study of Exploration of Early Development (SEED) CDC Study in the Center for Autism Research at the Children’s Hospital of Philadelphia (CHOP). She currently serves as a Pediatric Nurse Practitioner in the Clinical Genetics Center at CHOP. As a board certified pediatric nurse practitioner, Dr. Souders provides care for children and adolescents with neurodevelopmental disorders including autism spectrum disorder (ASD) and their families. Her clinical practice informs her teaching, research, and scholarship. She is a frequent national and international speaker. Dr. Souders’ research involves understanding the causes of insomnia in individuals with neurodevelopmental disorders and ASD and developing targeted interventions which promote sleep in these vulnerable populations.

Dr. Souders is an experienced educator who directs highly-regarded courses. Her lectures consistently receive high ratings for both quality and content. With her clinical background and hands-on experience with the autism population, she has accumulated tremendous clinical exemplars that she uses in connecting theory and research with practice in her teaching. Dr. Souders is the co- director of Integrated Nursing Care of Autism Spectrum Disorder, a series of three classes, NURS 641, NURS 642, NURS 643, which can earn a certificate or minor when all three courses are completed.

Dr. Souders’ research involves understanding the causes of insomnia in individuals with neurodevelopmental disorders and ASD and developing targeted interventions to promote sleep in these vulnerable populations. Dr. Souders serves as a Principal Investigator of Department of Defense:
Principal Investigator 7/1/2013-7/1-/2014
Department of Defense, Office of the Congressionally Directed Medical Research Program, 2013 AR120166, Feasibility of Tailored Behavioral Interventions for Insomnia in Children with Autism Spectrum Disorders

U01-MH087636-02 Emanuel (PI) 09/10/2010-5/31/2015 NIH
Brain-Behavior and Genetics Study of 22q11.2 Deletion
Dr. Souders will recruit and coordinate clinical activities for the 22q11.2 Deletion Syndrome subjects in the Brain-Behavior and Genetics Study of 22q11.2 Deletion. Dr. Souders will contribute to the interpretation of the clinical aspects of the study. Her expertise as a nurse is essential to the team for determining if subjects meet inclusion criteria and supporting this vulnerable population through the research process. Dr. Souders will participate in the development of the REDCAP database and supervise data entry. She will also assist the team with publications and presentations of study findings.

• Currently Funded Grants

• Center for Biobehavioral Research

• The Children's Hospital of Philadelphia


• 2013 Clinical Practice Award, Department of Biobehavioral Health
Sciences, University of Pennsylvania, School of Nursing

• 2009 American Academy of Sleep Medicine Young Investigator Forum
selected and presented at NIH, Sleep in Children with Autism.
Bethesda, Maryland

• 2007 Families Fighting Autism, Service Award, for tireless dedication to
children with Autism Spectrum Disorders and their families in the
Greater Philadelphia Area.

• 2002 Leadership Education in Neurodevelopmental and Related Disabilities Program (LEND), Research Symposium, Children’s Hospital of Philadelphia Research Award, Outstanding Interdisciplinary Collaboration Study, “Rett Syndrome: Profiles in Courage”

• 2000 SuPeerior People Award, Children’s Hospital of Philadelphia, Recognized for demonstrating compassion, family centered care, and innovation and service excellence.

• 1996 Pennsylvania Nurses Association and Albert Einstein Medical Center: Staff Nurse Recognition Award for Nursing Excellence

• 1996 Albert Einstein Medical Center, Meritorious Award for Professional Nursing

• 1996 Pennsylvania Nightingale Finalist Award: Education Category “STAT C-Section Simulations” Albert Einstein Medical Center, Philadelphia PA

• 1981 BSN Cum Laude, University of Pennsylvania

• Honors/Awards Details »

Publications (select year)
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