CURRENT GRANTS

Validating NQF Nursing-Sensitive Performance Measures
Robert Wood Johnson Foundation
58297
8/15/06-8/14/08
PI: Sean Clarke

Nurse Staffing and Adverse Events on Inpatient Units
National Institute of Nursing Research, NIH
R01-NR009068
8/1/05-1/30/08
PI: Eileen Lake
Using data on staffing, patient falls and pressure ulcers from 4,300 nursing units in 650 hospitals in the ANA-sponsored National Database of Nursing Quality Indicators, this study will strengthen the evidence base on how nurse staffing patterns and practice environments support the quality and safety of patient care.

Outcomes of Nurse Practice Environments
9/30/04-5/31/09
National Institute of Nursing Research, NIH
R01-NR-004513 PI:  Linda Aiken
This is a continuation of previous studies of hospital outcomes using new and existing data on nurse staffing, environments and nurse and patient outcomes. We will survey nurses working in over 800 hospitals in California, New Jersey and Pennsylvania, allowing us to explore changes in staffing and practice environments over time, across institutions and in different settings.

Neutropenia Outcomes: Nurse Staffing and Environment Effects
10/01/03-9/30/07
Oncology Nursing Society
PI: Christopher Friese
Co-Investigator: Linda Aiken, Julie Sochalski
The purpose of this study is to examine how modifiable features of nursing care delivery affect the hospital outcomes of neutropenic cancer patients. The specific aims are to examine the effects of patient-to-nurse ratios and the nurse practice environment on 1) 30 day from admission risk-adjusted mortality, 2) failure to rescue patients who develop complications after hospital admission, and 3) frequency of potentially preventable untoward clinical events.

Nursing Intervention for HIV Regimen Adherence Among Seriously Mentally Ill
National Institute of Nursing Research, NIH
R01-NR-08851
6/1/03-5/31/08
PI: Michael Blank
Co-Principal Investigator: Linda Aiken
Co-Investigator:  Nancy Hanrahan
The aim of this study is to show that a service model that integrates nursing care and case management will result in demonstrably better HIV treatment outcomes using CD4 and viral load as indicators, and significantly reduced risk behaviors using standardized behavioral self-reports.

Center for Nursing Outcomes Research (CNOR)
National Institute of Nursing Research, NIH
P30-NR-005043
2/1/00-4/30/10
PI and Center Director: Linda Aiken
Administrative Core Director: Linda Aiken
Research Core Director: Sean Clarke
Dissemination Director:   Mary Naylor
This Center grant supports the development of measures and methods for studying variation in patient outcomes, and applies them to the evaluation of the effectiveness of nursing care. The Center will advance nursing outcomes research across clinical specialties, the health-disease continuum, health care settings, and diverse populations, placing a high priority on minorities at risk. The CNOR supports three cores that provide technical assistance, access to data, linkages to researchers throughout the University, and developmental funds for pilot studies.

Advanced Training in Nursing Outcomes Research (T32)
National Institute of Nursing Research, NIH
T32-NR-007104
6/1/99-3/31/09
PI: Linda Aiken
This training program fosters nurse investigators at the pre-doctoral and postdoctoral levels in nursing outcomes research through a formal interdisciplinary program of pre-doctoral and postdoctoral study comprising the conceptual and empirical foundations and the methodological approaches and statistical tools of advanced outcomes research.

COMPLETED GRANTS

Hospital Restructuring: Implications for Patient Outcomes and Workforce Policy
Investigator Award in Health Policy Research
Robert Wood Johnson Foundation
9/1/99-12/31/04
PI: Linda Aiken
This is a Health Policy Research Investigator Award to provide support to Dr. Aiken to create a synthesis of her past research on hospital outcomes and workforce.

International Nurse Shortages and Nurse Migration
Commonwealth Fund
4/1/03-3/31/04
PI: Linda Aiken
This project is a synthesis of information on international nurse migration with the goal of documenting the extent of relocation and examining policy issues relevant to a globally mobile workforce.

International Comparisons of the Impact of Nursing on Hospital Quality of Care and Patient Outcomes
Commonwealth Fund
6/1/03-5/31/04
PI: Linda Aiken
This grant will support the cross-national analyses of data collected from roughly 750 hospitals in the US, Canada, UK, Germany and New Zealand to produce the first ever findings of the impact of nursing on quality of care and patient outcomes across countries with differently organized and financed health care systems.

Beyond Quick Fixes: Evidence-Based Policy Analysis of Strategies to Balance Supply and Educational Mix of Hospital Nurses
Robert Wood Johnson Foundation
2/15/04-2/14/05
PI: Linda Aiken
This grant will support a policy analysis of existing data sources to illuminate actions that could be taken by the Foundation, health care institutions, policymakers, and consumers to improve the outcomes of care at the bedside now and in the future.

The Effects of Organizational Climate on Hospital Patient and Nurse Safety
National Institute of Nursing Research, NIH
K01-NR-07895
7/1/02-6/30/05
PI: Sean Clarke
Mentor: Linda Aiken
The purpose of this study is to investigate organizational climate for nursing practice as a predictor of patient and nurse safety problems using existing patient and nurse data.

Hampton Penn Center to Reduce Health Disparities
9/30/02-6/30/04
National Institute of Nursing Research, NIH
P20-NR-008361
PI: Sean Clarke
The purpose of this study is to further explore health conditions for which outcomes differ between African-American patients and patients from other groups. The study replicates earlier pilot work on Pennsylvania hospitals and the analyses will be mostly descriptive and exploratory in nature.

Nursing Expertise Measures for Outcomes Research
7/1/00-6/30/04
National Institute of Nursing Research, NIH
K01-NR-00166
PI: Eileen Lake
Mentor: Linda Aiken
The major goals of this project are to develop survey measures of clinical nursing expertise and test the survey measures in outcomes research models. The survey measures will be developed using primary survey and narrative data collected from a purposive sample of staff nurses at the Hospital of the University of Pennsylvania.

Effect of Nurse Expertise on Patient Outcomes
7/03-6/04
University Research Foundation; Leonard Davis Institute of Health Economics; and Sigma Theta Tau Xi Chapter
PI: Eileen Lake
The purpose of this study is to refine the Clinical Nursing Expertise Survey and to test the feasibility of using National Database of Nursing Quality Indicators (NDNQI) hospitals to collect data on nurse sensitive outcomes.

Outcomes of Inpatient AIDS Care
National Institute of Nursing Research, NIH
R01-NR-02280
PI: Linda Aiken

Outcomes of Hospital-Dedicated AIDS Units
Agency for Health Care Policy and Research
R01-HS-08603
PI: Linda Aiken
This was a comparative, observational study of 40 inpatient AIDS units to collect data on organizational attributes and patient outcomes from a set of "demonstration" hospitals and controls.

Center for AIDS Research (CFAR)
National Institute of Allergy and Infectious Diseases, NIH
P30-AI-45008
PI: James Hoxie (University of Pennsylvania School of Medicine)
Co-Investigator and Director of the Behavioral and Social Sciences Core: Linda Aiken
This Core in Penn's Center for AIDS Research seeks to provide a structure for organizing Penn's substantial research in the behavioral and social sciences, and focusing those resources on HIV/AIDS-related research. The goal of the BSSC Core was to advance AIDS research by facilitating the inclusion of state-of-the-science theoretical and methodological contributions from the behavioral and social sciences across the full spectrum of CFAR research.

Nursing Workforce Policy Research
The Robert Wood Johnson Foundation
PI: Linda Aiken
This study provided policy-relevant information on Medicare support of nursing education.

How Nursing Affects the Volume-Outcomes Relationship
National Institute of Nursing Research, NIH and Agency for Healthcare Research and Quality
R01-NR-04513
7/97-7/31/04
PI: Linda Aiken
Co-Investigators: Sean Clarke, Douglas Sloane, Jeffrey Silber (Children's Hospital of Pennsylvania), Geoffrey Anderson (Institute for Clinical Evaluative Science, Toronto)
This is a competing continuation of an international study of hospital outcomes using data previously collected in the United States and two Canadian provinces to explore the extent to which better outcomes observed in high volume hospitals can be accounted for by nurse staffing and organizational climate.

American International Health Alliance Initiative to Institute Quality Standards in Four Hospitals in Russia and Armenia
International Hospital Quality Improvement Initiative
University Research Foundation; Population Studies Center Mellon Program; Pilot Study, National Institute of Nursing Research, NIH, P30-NR-05043
PI: Linda Aiken
This study adapted a highly successful program of accreditation for nursing excellence, the American Nurses Credentialing Center's (ANCC) Magnet Hospital Recognition Program (ANCC, 2000), to countries of the former Soviet Union, where accreditation and quality standards in health care are only beginning to be developed.

Rationing of Nursing Care in Swiss Hospitals and Its Effect on Patient Outcomes and Nurse Shortage
Swiss Federal Office for Social Security
PI: Sabina DeGeest (Director, Institute of Nursing Science at the University of Basel)
Co-Investigator: Linda Aiken
This study was a continuation of the international study of hospital outcomes using data from Switzerland to explore the extent to which better outcomes observed in high volume hospitals can be accounted for by nurse staffing and organizational climate.

Outcomes of Hospital Staffing
National Institute of Nursing Research, NIH
R01-NR-04513
PI: Linda Aiken
The purpose of this study was to determine whether hospital staffing is related to clinical outcomes, and if so, to determine the intermediate or operant mechanisms by which staffing influences and hospital organization influence outcomes. The grant also included a supplement that funds the same study in the U.K. and Canada, the idea being that hospital restructuring is widespread and strikingly similar in intent and design throughout North America and Europe.

The Effect of Health Care Working Conditions on Quality of Care
Agency for Healthcare Research and Quality, NIH
R01-HS-01005
9/30/01-9/29/04
PI: Ann Rogers
Co-Investigator: Linda Aiken
This countermeasures program will involve strategies used by other industries to minimize the adverse effects of fatigue, sleep loss and circadian rhythm disruption, and will be evaluated by pre- and post test measurements of vigilance and sleep/wake patterns.